Shawn's right about the off-centre nature of the room... a shame the door couldn't have been relocated, as one day you'll no doubt want to increase screen size. Try and keep that in mind with built-in speaker locations (remember, you could always get an accoustically-transparent screen and have all your current speakers behind an enormous cinemascope picture).
That row of windows is going to cause you a bit of grief too -- spend up big on very heavy window dressing, and look into "screen gain" (I believe grey screens are very good at hiding ambient light and increasing contrast).
One thing that struck me was the huge open space behind the viewers. If this is a full-time HT setup, why not have the builders put in a single wall behind the seating position, open at both ends. Just to give you something to fill the air behind you and encompass the room a little.
Finally... you have a sink in your room?
