While some folks might only use the PS3 remote to turn the console off and on, I regularly scan through the XMB GUI to access music, photos, and video stored on a Toshiba 320gb HDD internal upgrade. This gives me instant access to about 80 movies, 8 gigs of pics, and about 1,000 mp3s without moving a muscle. Just got a ps3toothfairy and really love it. Paired it with my Harmony 550 and got one remote running everything for under $200. Small, inconspicuous, and super easy to pair with the PS3 and Harmony remote. Highly recommended.
