I was just getting ready to post a question about this when I noticed that Kris75 had just made a post about the same problem. I have an MBox 2 Mini that would be perfect for using with REW (Mic preamp, Phantom power, etc) but I can't get it to work either. I've also tried it with TrueRTA with no results. I'm guessing that it's because both of these programs seem to default to Windows Sound and will not work with ASIO devices (?) though it does work with any kind of recording and editing software I throw at it (Adobe Audition and Premiere Pro, CuBase, and ProTools LE. Anybody have any ideas for me and Kris?