Certainly, if you are observing clipping in the red lights on the preamp/mixer, or if REW is warning of excessive levels on the input channels, then you need to tweak the input volume downward at either the preamp or the computer. Whenever you change these, you need to redo the Calibrate SPL step, because you have changed the REW perceived electrical levels while the physical audio levels were unchanged. Because I never know if someone or some other application has changed the levels, I find it best to run the Calibrate SPL step at the start of each session.
Of course, if you are just interested in making the graph have the normal average level of 75dB, you can change the offset to the data to achieve the level you want to see, and can use the Add offset to data button to permanently modify that measurement.
Bill