Nice looking room. One thing I notice is the seating area looks very close to the center of the room. That is, the couch is about the midway point between the fireplace/TV and back wall. This will be your first horror story in trying to achieve decent subwoofer bass. The midpoint of any room is where the bass waves of certain frequencies cancel each other. I'd plan to change the seating distance or as Wayne mentioned, be prepared to buy two subs. To his thoughts, I would even prewire for one sub up front and the other along the back wall somewhere. They don't need to be large. They just need to be of good quality. Some room treatments and bass trapping would certainly help. I know the drawing is only conceptual but some soft surfaces will be needed.
Speaking of cabling, run two of everything to the back wall. If one set of conductors fail, you're covered. Otherwise, you may be into ripping out large amounts of drywall. Been there, done that!
Speaking of cabling, run two of everything to the back wall. If one set of conductors fail, you're covered. Otherwise, you may be into ripping out large amounts of drywall. Been there, done that!