Only you can answer that question I'm afraid - the best any of us can do is give general advise and suggestions. We would need a lot more information before anyone can really assist though. Things like budget, usage (HT, music, gaming), listening habits (loud, quiet), room size (HxWxD), current speakers, physical size and/or WAF restrictions, etc.
Ascend 340 cmts for left, center, and right
Definitive 800 rears
Definitive 60 top middles
Polk psw 505 sub
Denon x1200w
Sony 65xbr900b
Size of room LxWxH
10.5x9.5x6.5
Budget is open so just want suggestions.